2020 POA Publications

Clinical validation of a machine-learning derived signature predictive of outcomes from first-line oxaliplatin-based chemotherapy in advanced colorectal cancer
Clinical Cancer Research

The Landscape of Glycogen Synthase Kinase-3 beta (GSK-3b) Genomic Alterations in Cancer
Molecular Cancer Therapeutics

Molecular Characteristics of BRCA1/2 and PALB2 Mutations in Pancreatic Ductal Adenocarcinoma
ESMO Open

Prevalence of Phosphatidylinositol-3-Kinase (PI3K) Pathway Alterations and Co-alteration of Other Molecular Markers in Breast Cancer
Frontiers in Oncology

Prevalence of class I-III BRAF mutations among 114,662 cancer patients in a large genomic database
Experimental Biology and Medicine

Molecular characterization of appendiceal goblet carcinoid
Molecular Cancer Therapeutics

Comprehensive genomic profiling of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs)
Clinical Cancer Research

Frequent Mutations of POT1 Distinguish Pulmonary Sarcomatoid Carcinoma From Other Lung Cancer Histologies
Clinical Lung Cancer

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases
Oncotarget

Rethinking Clinical Trials Reform During the COVID-19 Pandemic
JAMA Oncology

Primary CNS lymphoma commonly expresses immune
response biomarkers

Neuro-Oncology Advances

POT1 mutation spectrum in tumour types commonly diagnosed among POT1-associated hereditary cancer syndrome families
Journal of Medical Genetics

Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget’s disease
Cancer Medicine

Immune checkpoint expression, microsatellite instability, and mutational burden: Identifying immune biomarker phenotypes in uterine cancer
Gynecologic Oncology

Comprehensive tumor profiling reveals unique molecular differences between peritoneal metastases and primary colorectal adenocarcinoma
Journal of Surgical Oncology

Molecular variations in uterine carcinosarcomas identify therapeutic opportunities
International Journal of Gynecological Cancer

Molecular Analyses of Left‐ and Right‐Sided Tumors in Adolescents and Young Adults with Colorectal Cancer
The Oncologist

Relationship between MLH1 , PMS2 , MSH2 and MSH6 gene‐specific alterations and tumor mutational burden in 1057 microsatellite instability‐high solid tumors
International Journal of Cancer

WRN-mutated colorectal cancer is characterized by a distinct genetic phenotype
Cancers

The molecular profile of BRCA-mutated biliary tract cancers
ESMO Open – Cancer Horizons

Relationship Between Protein Biomarkers of Chemotherapy Response and Microsatellite Status, Tumor Mutational Burden and PD-L1 Expression in Cancer Patients
International Journal of Cancer

An Emerging Landscape for Canonical and Actionable Molecular Alterations in Primary and Metastatic Prostate Cancer
Molecular Cancer Therapeutics

Molecular Genomic Profiling of Adrenocortical Cancers
in Clinical Practice

Surgery

Population bias in somatic measurement of microsatellite instability status
Cancer Medicine

Actionable co-alterations in breast tumors with pathogenic mutations in the homologous recombination DNA damage repair pathway
Breast Cancer Research and Treatment